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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aa7459ce8bdb2a8e3cbe58e56b3b57a09c5315cc3138cb157357d16c56f44e9' 
  AND token = '7+6Fiz8I9PdwtR4FyB5/yLb5UO5lSJw3MqjKfBlzaPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}