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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01d7b0cfb5f1d8fa2ec688f2cb4770f071dd27c90c2f7ed73791dc669d5cc8f' 
  AND token = 'TuUV5EVm5Wnn3bU7SZsaHkJClIltc+qRRvrIjqhAsVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}