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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5851aa392a611941ef42ed7b4e27e27a04f630fe06c8a12442c58d13be4d43d5' 
  AND token = '38ATgLgd6cf4nUkJfv6+42D5lHLX9ALf9wrzEygb6WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}