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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78a3a1b5d04102252e393dbc8761cb365867fff8553f6cb6e685a31425675be' 
  AND token = 'ReXuebYgeJTJ9RRfoYeTj0x6XzkBYOTliLa7XL9MCcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}