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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1aeb809319ca2531d35c24ac36aaff6fcce76288cdfc6b45b163124b979393' 
  AND token = 'NimYoOK7Zf4Y/x2eD6HboETXWcr2F1wknhwCoQ1DVRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}