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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd90eb9003607b74e91bba00ba2d174f33d09c7b5a9d0d87b024108efc599e723' 
  AND token = '7FFOxCdNtkJfcEy/uoUJHbBdKGMxW0nYhfos0cM+nGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}