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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d410bf343b9feb0d59c8f499c4e16ddc2cb88ad750ace9199e236eeadb6de2c' 
  AND token = 'XggJJtwgDSDtJPB1h6v8UmIhcwR12GGF8gYSdglDTgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}