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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f774cb8d12a15609bd695ca970d37953c23207f69d004e019bb9b0ea45544130' 
  AND token = 'Vuho41yU8DiXsL6XqkRnGv4vkh7b6AV/0ZIyqE3p258=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}