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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33847cfcf52b4a66b3b8831bc61f4d9f476a7cc53c0d4b344f70913d1ac4394e' 
  AND token = '+KN7qwF0VGZ1HTm5eSvfcVxxGSmWNSXWLkEY/fOontU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}