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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5362cecec8d378c42179eb501cdb7f56f21d833bc97161568750f9bb1656a3af' 
  AND token = 'dP7aFRwBgaxAS7VCSKOmZZSbJeOhBxfWK9WB/5nhBLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}