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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129ff15e33a6e6dd3b05f0e802448dc2dd5e1a28dc8a85c3115f0a547ec80456' 
  AND token = '9kqDqU+LizrBva6sSAESxfrQWpCeN0V0G69fdze62TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}