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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01381eceb28cc474e9c8ae229fbd987096d6afb106b8468dc10cff62d8b44e24' 
  AND token = 'WKmxT9AIK0k2sC/Swacsv6nKc0GOFdtwE10EXmVJ3x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}