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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12892a97364cbc7c1e9cb09a698567345fa1839a3ea53b2a1e2f1fc334b5a218' 
  AND token = 'SbBb5G0Y/GLbeY9WuDelUJcS8hP/tbn8OhIPz4jquiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}