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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '736bb7d56a79f6ede8de21d6c3d07fc2628f1a1bc7c448e1397ab4c7c0761a5c' 
  AND token = 'Pk6b+EoFoCutmofDTeCu7b3HEnB6bPBiHCpy+k1MOWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}