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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67fd49e676ee7bd6d86e07117321d7ac0b87e714b78b4e5648d4be81e2acde29' 
  AND token = 'xpeyVRppeR3CF5BIngKr4v8c04UujDVhuNlm6eWfk2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}