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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb12e018b5769ebbedaa6673a74b4a7a128c7fc80af839e884a1f7e9fdbd700f' 
  AND token = 'FSzq1qak3ZRBt4tjeRbDv+aq595sQmXBqVwD2J5gk5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}