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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0a7d0d414db7756e793c7cfdd270c2e5ac5233f7afaeeecff4eccb42d5e021' 
  AND token = 'obz2X7pV4wWPyVSB04IrhfmCAiMBUsJTYzntVN9FaZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}