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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2372f7c084f545b6f1207b24bbb666999dd31977069760b960f8da19fa4ef073' 
  AND token = 'CQgBjVSRn7mm2016nu6labdE44l/KiC10RMl9w7wOCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}