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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5eda70ff2d4e862c42b664a9a4301bc00cc13e2eda5ff9f94c8b96da3343807' 
  AND token = 'A/ZAAwYJH9XP2SDPsFg2kMd54sZqbsHuYG1tk55J6rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}