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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5013a52b83d6ea6dc87ec5c684f304f0dc41b4f04db695c6e637b2ab52dff327' 
  AND token = 'TDta/RTMNqGHdYGeKyMzP5gyQiEQeGnz+Lm68saDJKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}