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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '205fa8349dc6c75ea7b2f101d28af254dfa48c20c6581f526f0c07b867071c64' 
  AND token = 'npimEV0g4WKWZIneOEVHT8lC/DqlKps2npaRY2W0yDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}