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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f7399900090e809522c0a730b37264218812f40ce7c606d70e32b5af534db2' 
  AND token = 's+cbpnviGV1EId5zQ4RIxnadnCxqGOzla8urPD5/k58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}