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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7ad56020a0bf3aed1f5ee9077110303088483db527214cc1201f8f33ad9e7c' 
  AND token = '11Ew/+meXpBDT+jX05Xi2piba9mcivsrQZYfelp21SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}