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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16d44956eed9272d60c268cda991200670d4dcd42c1636dd0b0faaf4deb4718' 
  AND token = 'n/0T/2QKfiUxPW7VgbOxMurcyMYGgFerYOtXLwCxxjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}