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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e75012905be500219d180ca8fed18f1597707961d89cc26d0c0c7a1e41fa683' 
  AND token = 'qlqP90JDUmKI0KvampP8SbQhuLLqWlKi+EBKxOpRoSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}