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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6f6edf6b26c91276e172a6a0786e17adfdb04bab89028c3d2e9bd059056a457' 
  AND token = 'AXBh6ibKKqVg/tTKl9vx9IDg+CsV3NPaOI8cg8kx4ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}