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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aec305975a6d50d911934606f93d2fad488e8d82bc88ef25d8b5c33b4358da11' 
  AND token = 'chJFW73myqiUHA2DXx2lHJaMoJ/IzybJE01dMHOCzAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}