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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cada1c12ae44dab269e92e245b8c517db94717a7396d8c69f1acd21c5fdf721' 
  AND token = 'X97bouUAHz0P3lxkuNiXAAfJpVmVzwSEf8l8endKeYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}