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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e48bdcb04f0f793feaa47bb56c908d3a101531d07bd77acb9c97914f1c6a9b' 
  AND token = 'fdMV+E2SuhZiG1veT38x2GUbpvCrO/60lAePjf5v+uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}