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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b85e5e718538f5fba9a513ae6f84824461a40ca0e9bfddaf7a1e54997907e3fc' 
  AND token = 'RO+KdfpZoAMrr0ap0tCoOioKKGRoErLfw9VU+XACv4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}