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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2c298f86339d21a89c0eda1407dc76177be03d883b234d3adf987d7dd8b900d' 
  AND token = 'R4S48zaReO2Yj38a8vki30BY+pmAf2wkaATDSkWpOCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}