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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22f97a6fbed4fab0bacbd378cd5d89de45180b34a29ce640f3b3a2c0c967509' 
  AND token = 'xNpm4FsX+OOpc64Zox0yRUXNLqIKXtkIH4KZljxFm2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}