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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b382b33fd2eb0a3d3ce4815b22a490cc53df205f8e546efa642975573e054c60' 
  AND token = 'JZLgFgzm6Jb4gCmLdGUSg3Eu0OhErAcfmKDcQ5040xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}