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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63dfbf1a7689e00a3a0cf81cb637f160a3cbccc69cda08ed3b907ff03e1567c' 
  AND token = 'UuCXRUCiVHTqKTo8CuUrvy1RXzDNkXIc899HvbjqAPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}