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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69b3e0fb9a05c4b9f49082a73da5fdfe54d1759412d8cfb4e6b346a430ae0297' 
  AND token = 'PsDZBMOn3KhVjbIUPRideAb0oVDjo48kvBZFi1FKi7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}