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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f2e0dd876ba53a52ddc92f925238306a43d9c4068ac35ad2615059d1965564f' 
  AND token = 'SUO0VvXMvGhe99w2KLh3TJQulKDuvb54NunDJHPDTYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}