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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55a34cc01ee68c7794af0e841cd2075a7362423e390f2494985a49e3433785ac' 
  AND token = '+NPRE6bn2AzuaiffM9ekWsLVbOsIREhVM3MCFs6/8zQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}