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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c9414aec9e7a1fbcfc7736d5b7279ff46d8863eed144be39ba12e4bf044484' 
  AND token = 'IqN+/jVQfAoVh1f0gJk6r+3q14RYyQV9PhcfKuZGdsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}