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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f910400d585825ac6955b487012cbefa3d69ef1d7e3beb90958ccaaf7f735d40' 
  AND token = 'RB6jQcZ+qSWdSCVOra7FDkSo0eGk/9rleTfR+Q5ZGL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}