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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66dce53b6ca228a46d30d0550adee3e8ecad12895f07ca17f6d8e078d99e060d' 
  AND token = 'WpyBczCp2+cg7D2OwoeLb6Ad6a97ZO1Bp4vQJfdAAzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}