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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3674e19f2d26e116c2010fff308be0e438959fe41009e02669a8bae2dbc797ca' 
  AND token = '5f7U8+9iuT1EGPIFQALoaAF61pLminsqhQCB19yNsn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}