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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a92e536843d55af5ebabbf9cbefd04256f7993b9f3f0b12df46e829a15dd109b' 
  AND token = '192Me622hpu1GtQXMsDtjnLat68c20i0v/nBYGJpjDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}