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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4cdcdae0bab1857750934130b12d94bf7ab5bc16b53b5ff1089ed676a8e754b' 
  AND token = 'oLkv4aV4E33+07G4s+kDr9nRjLJXDYmQnYZ0s8qBUlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}