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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c284dac0deaa8f83c389d22f6825b5274d30bf00c8ea84c5df33525bd44e1a4d' 
  AND token = 'dHB2x15dCsHqP88oCLcSsr9PmO2Xc+Do4bgOS5nHmQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}