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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4086bee9c43a66622ac371083e3e67fa7936088578ebf942a4c0f6262740d52' 
  AND token = 'zYwmxhdnWPmoesigSrJ7ZgmcpHi7kMqo1m6e00MiG0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}