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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e8cdfa55335e5a53a87f7b3662d188da3f2c88716c470d7b6ae4e880b2f3152' 
  AND token = 'a0en35gyCPlYtlVX6vgs/yB+YIPzRdZUg/JBBu0HIcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}