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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7458780910abc4719ee393b2e0cf3351430672f53935b9497ae8c98908e153a1' 
  AND token = '3HDPFjhZjnmZ2dkbnnh0M/vD1rnczDcHOL6KXSYlFYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}