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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec27c5221f1df93c41975c72779b2970046ed50ac969d37b54ce8e1114747ec3' 
  AND token = 'wlDZXKBKLiWk1clFs87M56ZxlVgfH+N/tT8PGZzo6QA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}