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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff335fd066b0d81c7acad8df4ff73ba573e18e2bf0db78d5896567ba7b9da7ad' 
  AND token = 'TehVNGGL3kBGqrUH8x0zkksmEGeMtKR9MLU+c0bDrNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}