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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ef2a8ba14e4a9cfe83dee10643d0a0fdea8fcee65479a8ed1cf882511858c0' 
  AND token = 'ueqa5m2maSnmEpPAMMj4pTX+Op8Y7vsHMKYdwJ1THv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}